diff --git a/app/src/protyle/wysiwyg/keydown.ts b/app/src/protyle/wysiwyg/keydown.ts
index 1d05aee56..82261962d 100644
--- a/app/src/protyle/wysiwyg/keydown.ts
+++ b/app/src/protyle/wysiwyg/keydown.ts
@@ -699,6 +699,27 @@ export const keydown = (protyle: IProtyle, editorElement: HTMLElement) => {
                     return;
                 }
             }
+            // 行首转义符前删除 https://github.com/siyuan-note/siyuan/issues/6092
+            if (range.startOffset === 0 &&
+                previousSibling && previousSibling.parentElement.getAttribute("data-type").indexOf('backslash') > -1 &&
+                previousSibling.nodeType !== 3 && (previousSibling as HTMLElement).outerHTML === "<span>\\</span>" &&
+                !hasPreviousSibling(previousSibling)) {
+                range.setStartBefore(previousSibling.parentElement);
+                removeBlock(protyle, nodeElement, range);
+                event.stopPropagation();
+                event.preventDefault();
+                return;
+            }
+            // 光标位于转义符前 F5 后，rang 和点击后的不同，也需进行判断
+            if (range.startOffset === 1 && range.startContainer.nodeType !== 3 &&
+                range.startContainer.parentElement.getAttribute("data-type").indexOf('backslash') > -1 &&
+                !hasPreviousSibling(range.startContainer.parentElement)) {
+                range.setStartBefore(range.startContainer.parentElement);
+                removeBlock(protyle, nodeElement, range);
+                event.stopPropagation();
+                event.preventDefault();
+                return;
+            }
             const imgSelectElement = protyle.wysiwyg.element.querySelector(".img--select");
             if (protyle.wysiwyg.element.querySelector(".protyle-wysiwyg--select")) {
                 removeBlock(protyle, nodeElement, range);